Vitamin B6, or pyridoxine, is a water-soluble vitamin found naturally in many foods, as well as added to foods and supplements. Pyridoxal 5’ phosphate (PLP) is the active coenzyme form and most common measure of B6 blood levels in the body. PLP is a coenzyme that assists more than 100 enzymes to perform various functions, including the breakdown of proteins, carbohydrates, and fats; maintaining normal levels of homocysteine (since high levels can cause heart problems); and supporting immune function and brain health. 

Vitamin B6 has been widely studied for its role in disease prevention. The vitamin in supplement form shows the most promise for the treatment of pregnancy-induced nausea, but such use should only occur under the supervision of a physician. Adequate blood levels of B6 may be associated with lower risk of cancers, compared to low blood levels.

Vitamin B6 is found in a variety of animal and plant foods:

>Beef liver

>Tuna

>Salmon

>Fortified cereals

>Chickpeas

>Poultry

>Some vegetables and fruit, especially dark leafy greens, bananas, papayas, oranges, and cantaloupe